🧬

Built with molecular scientists & geneticists

The right genetic test,
decided in seconds.

See how a clinical chart becomes an order-ready genetic-testing recommendation — step by step.

Step 01 · Ingest

Drop in any chart

Notes, PDFs, scanned records — or five patients at once.

Step 02 · Extract

Read like a clinician

Diagnoses, medications, family history and phenotype — structured in seconds.

DxRxFHxPhe
Step 03 · Reason

Match every panel

Across pharmacogenomics, cancer, neurology, metabolic and cardio.

Step 04 · Validate

Prove it's coverable

Each panel backed by a documented ICD-10 and clinical safety gates.

Step 05 · Recommend

Order with confidence

Qualified panels, each with a clear, defensible rationale.

💊

Pharmacogenomics

Explore
🎗️

Hereditary cancer

Explore
🧠

Neurology

Explore
🔬

Metabolic disease

Explore
CPIC-aligned pharmacogenomics ICD-10 coding integrity Deterministic & auditable Coverage-aware recommendations Gene–disease validity Batch-ready workflow
ScreenMyGene · Recommendations
● Qualified

Comprehensive Pharmacogenomic Panel

Two CPIC drug–gene interactions identified from the active medication list; ordering supported by a documented indication.

Drug–gene pairs: 2Indication: documentedCoverage: policy-aligned
● Potentially qualified

Hereditary Breast & Ovarian Cancer Panel

Personal-history coding present; family history supportive. Confirm testing criteria before ordering.

ICD-10: matchedFamily history: supportive
The platform

A reasoning engine,
not a lookup table.

ScreenMyGene converts unstructured clinical documentation into a defensible genetic-testing recommendation — reasoning over the whole chart, not searching a catalog.

  • Reads diagnoses, medications, family history, phenotype and prior workup
  • Surfaces qualified and potentially-qualified panels — with the reasoning
  • Anchors every recommendation to a documented, matching diagnosis code
  • Explains its rationale in plain language — and aloud, in a geneticist's voice
Open the portal →
How it works

From chart to recommendation,
in a single pass.

Paste a note, upload a record, or batch several patients at once. ScreenMyGene does the reading, the reasoning, and the coding.

01

Ingest

Paste a note, upload a PDF, or batch up to five charts. OCR lifts text from scanned records and requisitions.

02

Extract

A clinical language layer structures diagnoses, medications, family history, phenotype and prior testing.

03

Reason

Tiered rule engines map the chart to qualifying panels across every supported specialty.

04

Validate

A documented, non-generic ICD-10 must support each panel; safety gates and coverage rules apply.

05

Recommend

Qualified and potentially-qualified panels arrive with a clear, defensible rationale.

ScreenMyGene · Analysis history
Patient A
Pharmacogenomics · Neurology
2 qualified
Patient B
Hereditary cancer
1 potential
Patient C
Metabolic
1 qualified
Batch workflow

Run a whole clinic
in one pass.

Upload up to five patients, review and edit each extracted chart, add labs, then analyze together. Every result lands in your history, one click apart.

  • Per-patient review before anything runs
  • Live progress, accurate counts, nothing lost
One pass
1
Ingest
Any chart, in seconds
NotesPDFsScansBatch ×5
2
Extract
Read like a clinician
DiagnosesMedicationsFamily historyPhenotype
3
Reason
Match every panel
PGxCancerNeuroMetabolicCardio
4
Validate
Prove it's coverable
ICD-10 codeCMS coverageSafety gates
5
Order-ready
Defensible rationale
Qualified panelsDocumented DxPolicy-aligned

A chart enters unstructured and leaves as a recommendation anchored to a diagnosis code and a coverage policy. Every stage is inspectable — never a single opaque jump.

Technology

Built on the evidence base
clinicians already trust.

Every recommendation traces to an established source of truth — never a black box.

🧫

CPIC pharmacogenomics

Drug–gene guidance from the Clinical Pharmacogenetics Implementation Consortium. Panels qualify from real medication exposures — never a single gene alone.

ICD-10-CM coding integrity

Diagnosis codes are validated to the character. A recommendation stands only when the chart carries a documented, matching, non-generic code.

🧬

Gene–disease validity

Panel content is curated against ClinGen, GenCC and PanelApp-style validity, so every test reflects an established gene–disease relationship.

📋

Coverage & medical necessity

Logic aligned to Medicare local and national coverage determinations and payer medical-necessity criteria, so recommendations are order-ready.

DeterministicSame chart, same result — reproducible by design.
TransparentEvery panel shows the diagnosis that supports it.
Safety-gatedStructural-, reversible-cause and age constraints applied.
Coding-cleanBilling codes never appear on the clinical recommendation.
Evidence, combined
CPIC ICD-10-CM Gene validity Coverage One recommendation traceable to every source
Four independent sources of truth are evaluated together. A recommendation only stands when all of them support it — and each contribution stays traceable.
Clinical areas

Specialist coverage across
the genomic menu.

💊

Pharmacogenomics

CPIC-aligned drug–gene matching from the active medication list.

Qualifies multi-gene PGx panels when supported drug exposures are present — and never emits a lone CYP gene as a standalone test.

🎗️

Hereditary cancer

Panel selection grounded in personal and family history.

Aligns to professional-society testing criteria; family history is treated as a supportive factor, not a sole qualifier.

🧠

Neurology

Hereditary neuropathy, epilepsy and related presentations.

Tier-1 evaluators with structural- and reversible-cause safety gates that keep recommendations clinically appropriate.

🔬

Metabolic disease

Inherited metabolic and storage disorders.

Phenotype- and diagnosis-driven logic for conditions such as Wilson disease and related inborn errors of metabolism.

❤️

Cardiogenetics

Inherited cardiac and related conditions.

Curated gene–disease validity keeps cardiogenetic panels aligned to established relationships and current frameworks.

📁

Batch review

Up to five patients in a single, reviewable pass.

Read and edit each extracted chart, add labs, then analyze together — results land in your history, one click apart.

Who it's for

Wherever the right test
needs to be found — fast.

Molecular & genomic labs

Fewer denials, cleaner orders

Triage inbound orders, cut avoidable denials, and standardize medical-necessity documentation before a sample is run.

Medical directors

A defensible rationale, every time

A consistent, auditable basis behind every recommended panel — reproducible across the team and ready for review.

Genetic counselors

More time with patients

Faster chart triage means less time reconciling catalogs and coverage rules, and more time where it matters.

Ordering clinicians

Specialist-grade selection at the point of care

The right test without memorizing the genomic menu — surfaced with the reasoning behind it.

Precision-medicine programs

Rigor that scales

Policy-aware genomic ordering across a population, without trading away consistency or safety.

Revenue-integrity teams

Coding-backed from the start

Recommendations arrive supported by a documented diagnosis, reducing denials and downstream rework.

Trust & safety

Decision support you
can stand behind.

🔒

Support, not diagnosis

ScreenMyGene assists qualified professionals; it never replaces independent clinical judgment.

🧾

Auditable by design

Every recommendation traces back to the finding and the code that produced it.

🛡️

Privacy-minded

Designed for de-identified and synthetic data in evaluation, and controlled clinical environments in use.

Reproducible by design
Same chart, run three times ScreenMyGene Probabilistic
Run the same chart three times and a deterministic engine returns the same result three times. Probabilistic systems drift — which is a problem when the output has to be defended on review.
FAQ

Common questions about genetic-test decision support

What is genetic test utilization management?

It is the process of making sure genetic and molecular tests are ordered appropriately, coded correctly, and supported by medical-necessity and payer-coverage criteria before a sample is run — reducing avoidable denials and inappropriate testing.

What does ScreenMyGene do?

ScreenMyGene reads a clinical chart, extracts diagnoses, medications, family history and phenotype, and surfaces the genetic and pharmacogenomic panels the patient qualifies for — each anchored to a documented ICD-10-CM code and checked against CMS coverage policy. Deterministic, auditable, and coding-clean.

Who is ScreenMyGene for?

Molecular and genomic laboratories, medical directors, genetic counselors, ordering clinicians, precision-medicine programs, and revenue-integrity/RCM teams. It is a decision-support tool for professionals — not a consumer DNA test.

How does it reduce genetic testing denials?

It anchors every recommended panel to a documented, matching ICD-10-CM code and aligns it to Medicare LCD/NCD and payer medical-necessity criteria, so orders are order-ready and defensible before submission rather than corrected after a denial.

Does ScreenMyGene replace clinical judgment?

No. It is clinical decision support that assists qualified professionals. It does not provide a diagnosis and does not replace independent clinical judgment; test-eligibility and coverage decisions remain with the ordering provider and applicable payer policy.

What evidence base does it use?

Every recommendation traces to established sources: CPIC for pharmacogenomics, ClinGen/GenCC/PanelApp-style gene-disease validity for panel content, ICD-10-CM for coding, and Medicare LCD/NCD coverage policy — never a black box.

Which clinical areas does it cover?

Pharmacogenomics, hereditary cancer, neurology, inherited metabolic disease, and cardiogenetics — with safety gates (structural, reversible-cause, and age constraints) applied so recommendations stay clinically appropriate.

Is it deterministic and auditable?

Yes. The same chart produces the same result, and every recommended panel shows the finding and the diagnosis code that produced it — so the rationale is reproducible across a team and ready for review.

Bring specialist-grade test selection to every order.